Climate change brings various negative effects to human daily life and production, and thus poses a threat to sustainable urban development. Spatial planning has been widely accepted as an effective strategy responding to climate change and city safety problems caused by climate change and extreme weather events. However, little information is available on the combination of spatial planning and climate change adaptation. This paper focuses on “how to integrate climate change into spatial planning”, and summarizes the spatial planning experience of cities and researches in the literature from the perspectives of spatial planning goal-setting, content-setting and planning methods. In summary, first, spatial planning goal-setting should combine concept of resilient city with climate change adaptation; second, planning content should add climate change impact assessment, and integrate the assessment results into infrastructure layout, urban spatial pattern design, ecological security pattern construction, local regulation and policy as well as planning coordination. In terms of planning methods, scenario planning, dynamic cycle adjustment and community participation should be enhanced in the process of decision-making. In addition, on the basis of summarizing the research reviews at home and abroad, this paper points out that the research on spatial planning adapting to climate change from interdisciplinary perspectives are far from sufficient. Besides, the coverage of research scale and research object is incomplete. Herce, this paper proposes several issues that need to be studied urgently, namely quantitative evaluation of spatial influence of climate change, ideal spatial pattern adapting to climate change, best adapting practices at home and abroad, and rationalizing and validating pathways of dynamic adjustment in spatial planning adapting to climate change.